A dual detector β-ray imaging probe with γ-ray background suppression for use in intra-operative detection of radiolabeled tumors
The basic concepts for a dual detector β+ imaging probe incorporating a method of γ-ray background suppression were evaluated. The test devices consisted of a 1.2 cm2 β+ imaging CaF2(Eu) scintillator disk optically coupled to a 1.7 mm thick, area-matched transparent diffuser disk, which in turn was coupled to sets of 2 × 2 or 4 × 4 mm2 by 10 mm long BGO, GSO or LSO scintillators, which acted as both γ-detectors as well as light guides for the CaF2(Eu) scintillation light, which in turn are attached to a fiber optic bundle coupled to a multichannel photomultiplier. Pulse shape discrimination allowed identification of the detector of interaction and coincidence between the two detectors allowed selection of β+ -only events. This type imaging detector system was shown to be capable of producing high-resolution images of β+ distributions while suppressing the events due to the 511 keV annihilation radiation background. GSO was found to be the detector of choice for this application. © 1998 Elsevier Science B.V. All rights reserved.
Hoffman, EJ; Tornai, MP; Levin, CS; MacDonald, LR; Holdsworth, CH
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