Comparison of macular versus paramacular retinal sensitivity to femtosecond laser pulses.

Journal Article (Journal Article)

Single 130 fs laser pulses in the near-IR (800 nm) were used to create ophthalmoscopically viewed minimum visible lesions (MVLs) within the macular and paramacular regions in rhesus monkey eyes. MVL thresholds at 1 and 24 h are reported as the 50% probability for damage (ED50) together with their fiducial limits at the 95% confidence level. These measured thresholds are compared with previously reported thresholds for near-IR and visible wavelengths for both macular and paramacular areas. Threshold doses were lower at the 24 h reading than at the 1 h reading for both retinal regions and the ED50s for the macula were slightly lower than for the paramacula. We measured the 24 h MVL ED50 thresholds to be 0.35 and 0.55 microJ for the macular and paramacular areas, respectively. The combined data for both areas yielded a threshold of 0.45 microJ.

Full Text

Duke Authors

Cited Authors

  • Cain, CP; Toth, CA; Thomas, RJ; Noojin, GD; Carothers, V; Stolarski, DJ; Rockwell, BA

Published Date

  • July 2000

Published In

Volume / Issue

  • 5 / 3

Start / End Page

  • 315 - 320

PubMed ID

  • 10958618

International Standard Serial Number (ISSN)

  • 1083-3668

Digital Object Identifier (DOI)

  • 10.1117/1.430002


  • eng

Conference Location

  • United States