Intercalated discs as a cause for discontinuous propagation in cardiac muscle: a theoretical simulation.


Journal Article

A theoretical model of a cardiac muscle fiber (strand) based on core conductor principles and which includes a periodic intercalated disc structure has been developed. The model allows for examination of the mechanism of electrical propagation in cardiac muscle on a microscopic cell-to-cell level. The results of the model simulations demonstrate the discontinuous nature of electrical propagation in cardiac muscle and the inability of classical continuous cable theory to adequately describe propagation phenomena in cardiac muscle.

Full Text

Cited Authors

  • Diaz, PJ; Rudy, Y; Plonsey, R

Published Date

  • January 1, 1983

Published In

Volume / Issue

  • 11 / 3-4

Start / End Page

  • 177 - 189

PubMed ID

  • 6670783

Pubmed Central ID

  • 6670783

Electronic International Standard Serial Number (EISSN)

  • 1573-9686

International Standard Serial Number (ISSN)

  • 0090-6964

Digital Object Identifier (DOI)

  • 10.1007/bf02363285


  • eng