The differential effects of 200, 591, and 2,450 MHz radiation on rat brain energy metabolism.

Journal Article (Journal Article)

Three key compounds in brain energy metabolism have been measured during and after exposure to continuous wave radiofrequency radiation at 200, 591, and 2,450 MHz. Frequency-dependent changes have been found for all three compounds. Changes in NADH fluorescence have been measured on the surface of a surgically uncovered rat brain during exposure. At 200 and 591 MHz, NADH fluorescence increased in a dose-dependent manner between approximately 1 and 10 mW/cm2, then became constant at higher exposures. There was no effect at 2,450 MHz. Levels of ATP and CP were measured in whole brain after exposure. The ATP levels were decreased at 200 and 591 MHz but not at 2,450 MHz. The CP levels decreased only at 591 MHz. The effect of duration of exposure (up to 5 min) was investigated for all compounds at 200 MHz and 2,450 MHz, and exposures to 20 minutes were examined at 591 MHz. Temperature in the rat brain was essentially constant for all exposures. A general mechanism for inhibition of the mitochondrial electron transport chain and the CP-kinase reaction pathway by radiofrequency radiation has been proposed.

Full Text

Duke Authors

Cited Authors

  • Sanders, AP; Joines, WT; Allis, JW

Published Date

  • 1984

Published In

Volume / Issue

  • 5 / 4

Start / End Page

  • 419 - 433

PubMed ID

  • 6517961

International Standard Serial Number (ISSN)

  • 0197-8462

Digital Object Identifier (DOI)

  • 10.1002/bem.2250050407


  • eng

Conference Location

  • United States