Non-immune hydrops after 20 weeks' gestation: review of 10 years' experience with suggestions for management.

Journal Article (Journal Article)

OBJECTIVE: To analyze the etiologies and outcomes for a southeastern section of the United States, and to organize an efficient approach to evaluation. METHODS: We reviewed 82 cases of non-immune hydrops presenting after 20 weeks' gestation over a 10-year period. RESULTS: Overall perinatal mortality was 86.6%. Fetuses diagnosed with hydrops before 24 weeks' gestation had a perinatal mortality of 95%, with nearly one-third having abnormal karyotypes. The etiology of hydrops diagnosed after 24 weeks' gestation was more likely to remain idiopathic or to be related to cardiothoracic abnormalities. CONCLUSION: Before 24 weeks' gestation, the high risk of mortality and abnormal karyotype justifies offering families funipuncture in the hope of finding a treatable cause of non-immune hydrops. After 24 weeks' gestation, when fewer abnormal karyotypes are found, funipuncture may also be pivotal in diagnosing the cause of non-immune hydrops.

Full Text

Duke Authors

Cited Authors

  • McCoy, MC; Katz, VL; Gould, N; Kuller, JA

Published Date

  • April 1995

Published In

Volume / Issue

  • 85 / 4

Start / End Page

  • 578 - 582

PubMed ID

  • 7898837

International Standard Serial Number (ISSN)

  • 0029-7844

Digital Object Identifier (DOI)

  • 10.1016/0029-7844(94)00444-i


  • eng

Conference Location

  • United States