Non-immune hydrops after 20 weeks' gestation: review of 10 years' experience with suggestions for management.
Journal Article (Journal Article)
OBJECTIVE: To analyze the etiologies and outcomes for a southeastern section of the United States, and to organize an efficient approach to evaluation. METHODS: We reviewed 82 cases of non-immune hydrops presenting after 20 weeks' gestation over a 10-year period. RESULTS: Overall perinatal mortality was 86.6%. Fetuses diagnosed with hydrops before 24 weeks' gestation had a perinatal mortality of 95%, with nearly one-third having abnormal karyotypes. The etiology of hydrops diagnosed after 24 weeks' gestation was more likely to remain idiopathic or to be related to cardiothoracic abnormalities. CONCLUSION: Before 24 weeks' gestation, the high risk of mortality and abnormal karyotype justifies offering families funipuncture in the hope of finding a treatable cause of non-immune hydrops. After 24 weeks' gestation, when fewer abnormal karyotypes are found, funipuncture may also be pivotal in diagnosing the cause of non-immune hydrops.
Full Text
Duke Authors
Cited Authors
- McCoy, MC; Katz, VL; Gould, N; Kuller, JA
Published Date
- April 1995
Published In
Volume / Issue
- 85 / 4
Start / End Page
- 578 - 582
PubMed ID
- 7898837
International Standard Serial Number (ISSN)
- 0029-7844
Digital Object Identifier (DOI)
- 10.1016/0029-7844(94)00444-i
Language
- eng
Conference Location
- United States