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A fetus with sirenomelia, omphalocele, and meningomyelocele, but normal kidneys.

Publication ,  Journal Article
McCoy, MC; Chescheir, NC; Kuller, JA; Altman, GC; Flannagan, LM
Published in: Teratology
August 1994

Sirenomelia, which has been reported for more than 450 years, is the most severe form of caudal dysplasia. This disorder is classically associated with agenesis or severe dysplasia of the urinary tract. A 27-year-old gravida 3 para 0020 presented at 19 weeks' gestation with monoamniotic twins, one normal and one with sirenomelia. The pregnancy miscarried following invasive diagnostic testing. Autopsy confirmed the findings of sirenomelia, meningomyelocele, omphalocele, persistent cloaca, and two normal kidneys. The abnormalities accompanying sirenomelia appear as a spectrum. The pathogenic theories of sirenomelia are reviewed in light of this case with normal kidneys.

Duke Scholars

Published In

Teratology

DOI

ISSN

0040-3709

Publication Date

August 1994

Volume

50

Issue

2

Start / End Page

168 / 171

Location

United States

Related Subject Headings

  • Twins, Monozygotic
  • Pregnancy
  • Meningomyelocele
  • Kidney
  • Humans
  • Hernia, Umbilical
  • Genetics & Heredity
  • Female
  • Ectromelia
  • Diseases in Twins
 

Citation

APA
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ICMJE
MLA
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McCoy, M. C., Chescheir, N. C., Kuller, J. A., Altman, G. C., & Flannagan, L. M. (1994). A fetus with sirenomelia, omphalocele, and meningomyelocele, but normal kidneys. Teratology, 50(2), 168–171. https://doi.org/10.1002/tera.1420500212
McCoy, M. C., N. C. Chescheir, J. A. Kuller, G. C. Altman, and L. M. Flannagan. “A fetus with sirenomelia, omphalocele, and meningomyelocele, but normal kidneys.Teratology 50, no. 2 (August 1994): 168–71. https://doi.org/10.1002/tera.1420500212.
McCoy MC, Chescheir NC, Kuller JA, Altman GC, Flannagan LM. A fetus with sirenomelia, omphalocele, and meningomyelocele, but normal kidneys. Teratology. 1994 Aug;50(2):168–71.
McCoy, M. C., et al. “A fetus with sirenomelia, omphalocele, and meningomyelocele, but normal kidneys.Teratology, vol. 50, no. 2, Aug. 1994, pp. 168–71. Pubmed, doi:10.1002/tera.1420500212.
McCoy MC, Chescheir NC, Kuller JA, Altman GC, Flannagan LM. A fetus with sirenomelia, omphalocele, and meningomyelocele, but normal kidneys. Teratology. 1994 Aug;50(2):168–171.

Published In

Teratology

DOI

ISSN

0040-3709

Publication Date

August 1994

Volume

50

Issue

2

Start / End Page

168 / 171

Location

United States

Related Subject Headings

  • Twins, Monozygotic
  • Pregnancy
  • Meningomyelocele
  • Kidney
  • Humans
  • Hernia, Umbilical
  • Genetics & Heredity
  • Female
  • Ectromelia
  • Diseases in Twins