Obsessive-compulsive disorder in a birth cohort of 18-year-olds: prevalence and predictors.

Journal Article (Journal Article)


To report descriptive epidemiological information on obsessive-compulsive disorder (OCD) in an unselected birth cohort of 930 males and females, aged 18 years.


An epidermiological study of the prevalence of self-reported OCD at age 18, and a longitudinal analysis of the prospective predictors of OCD.


Using the Diagnostic Interview Schedule, the authors found a 1-year prevalence rate of 4%, with a male-female ratio of 0.7:1. The majority of OCD cases met criteria for a comorbid disorder, most commonly depression (62%), social phobia (38%), and substance dependence (alcohol 24%, marijuana 19%).


Data collected on the sample from birth to age 18 years indicated that many childhood risk factors theorized in the literature did not predict OCD in this sample. However, a history of depression and substance use were prospective risk factors for OCD.

Full Text

Duke Authors

Cited Authors

  • Douglass, HM; Moffitt, TE; Dar, R; McGee, R; Silva, P

Published Date

  • November 1995

Published In

Volume / Issue

  • 34 / 11

Start / End Page

  • 1424 - 1431

PubMed ID

  • 8543509

Electronic International Standard Serial Number (EISSN)

  • 1527-5418

International Standard Serial Number (ISSN)

  • 0890-8567

Digital Object Identifier (DOI)

  • 10.1097/00004583-199511000-00008


  • eng