Acute pulmonary embolism: artificial neural network approach for diagnosis.

Journal Article (Journal Article)

PURPOSE: To investigate use of an artificial neural network (ANN) as a computer-aided diagnostic (CAD) tool for predicting pulmonary embolism (PE) from ventilation-perfusion lung scans and chest radiographs. MATERIALS AND METHODS: The data base consisted of cases extracted from the collaborative study of the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED). Initially, scan findings from 1,064 patients (383 with PE, 681 without PE) were used to train and test the network by using the "jackknife" method. Then, a receiver-operating-characteristic analysis was applied to compare the performance of the network with that of the physicians involved in the PIOPED study. RESULTS: The ANN significantly outperformed the physicians involved in the PIOPED study (two-tailed P value = .01). CONCLUSION: The findings suggest that an ANN can form the basis of a CAD system to assist physicians with the diagnosis of PE.

Full Text

Duke Authors

Cited Authors

  • Tourassi, GD; Floyd, CE; Sostman, HD; Coleman, RE

Published Date

  • November 1993

Published In

Volume / Issue

  • 189 / 2

Start / End Page

  • 555 - 558

PubMed ID

  • 8210389

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.189.2.8210389


  • eng

Conference Location

  • United States