Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes.

Journal Article

The T-cell receptor (TCR) gamma polypeptide is expressed associated with CD3 (T3) on the surface of normal human peripheral blood lymphocytes. These cells function as non-MHC-restricted cytotoxic T lymphocytes (CTL)and thus may play an important role in host immune defence. The TCR gamma polypeptide occurs as a dimer in at least two molecular forms based on the absence or presence of disulphide linkage. These forms use TCR gamma polypeptides with strikingly different peptide backbone sizes.

Full Text

Duke Authors

Cited Authors

  • Brenner, MB; McLean, J; Scheft, H; Riberdy, J; Ang, SL; Seidman, JG; Devlin, P; Krangel, MS

Published Date

  • February 19, 1987

Published In

Volume / Issue

  • 325 / 6106

Start / End Page

  • 689 - 694

PubMed ID

  • 3102967

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/325689a0

Language

  • eng

Conference Location

  • England