Identification of a putative second T-cell receptor.
Framework monoclonal antibodies have identified a population of human lymphocytes that express the T3 glycoprotein but not the T-cell receptor (TCR) alpha- and beta-subunits. Chemical crosslinking experiments reveal that these lymphocytes express novel T3-associated polypeptides, one of which appears to be the product of the T gamma gene. The other polypeptide may represent a fourth TCR subunit, designated T delta.
Brenner, MB; McLean, J; Dialynas, DP; Strominger, JL; Smith, JA; Owen, FL; Seidman, JG; Ip, S; Rosen, F; Krangel, MS
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