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Pulmonary cytology of the acquired immune deficiency syndrome: an analysis of 36 cases.

Publication ,  Journal Article
Duggan, MA; Pomponi, C; Robboy, SJ
Published in: Diagn Cytopathol
September 1986

The infectious pathogens and associated cellular reactions in 75 pulmonary cytological specimens obtained largely by fiberoptic bronchoscopy from 36 patients with the acquired immune deficiency syndrome are described and correlated with the biopsy specimens. An opportunistic pathogen was diagnosed in 33% of cytological preparations. Pneumocystis carinii was encountered most frequently; Cryptococcus neoformans and cytomegalovirus were also seen. The polymorphonuclear neutrophil was the predominant inflammatory cell. Cells of secondary import were bronchial cells and type II pneumocytes with atypia and hyperplasia. Bronchoalveolar lavage had the highest yield, positive predictive value, and sensitivity for all pathogens and for P. carinii. An opportunistic pathogen was diagnosed in 69% of patients utilizing histological material and in 33% using cytological samples; the rate of diagnosis increased to 72% when the samples were combined.

Duke Scholars

Published In

Diagn Cytopathol

DOI

ISSN

8755-1039

Publication Date

September 1986

Volume

2

Issue

3

Start / End Page

181 / 186

Location

United States

Related Subject Headings

  • Therapeutic Irrigation
  • Pulmonary Alveoli
  • Pneumonia, Pneumocystis
  • Pathology
  • Opportunistic Infections
  • Middle Aged
  • Male
  • Lung
  • Humans
  • Histocytochemistry
 

Citation

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ICMJE
MLA
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Duggan, M. A., Pomponi, C., & Robboy, S. J. (1986). Pulmonary cytology of the acquired immune deficiency syndrome: an analysis of 36 cases. Diagn Cytopathol, 2(3), 181–186. https://doi.org/10.1002/dc.2840020302
Duggan, M. A., C. Pomponi, and S. J. Robboy. “Pulmonary cytology of the acquired immune deficiency syndrome: an analysis of 36 cases.Diagn Cytopathol 2, no. 3 (September 1986): 181–86. https://doi.org/10.1002/dc.2840020302.
Duggan MA, Pomponi C, Robboy SJ. Pulmonary cytology of the acquired immune deficiency syndrome: an analysis of 36 cases. Diagn Cytopathol. 1986 Sep;2(3):181–6.
Duggan, M. A., et al. “Pulmonary cytology of the acquired immune deficiency syndrome: an analysis of 36 cases.Diagn Cytopathol, vol. 2, no. 3, Sept. 1986, pp. 181–86. Pubmed, doi:10.1002/dc.2840020302.
Duggan MA, Pomponi C, Robboy SJ. Pulmonary cytology of the acquired immune deficiency syndrome: an analysis of 36 cases. Diagn Cytopathol. 1986 Sep;2(3):181–186.
Journal cover image

Published In

Diagn Cytopathol

DOI

ISSN

8755-1039

Publication Date

September 1986

Volume

2

Issue

3

Start / End Page

181 / 186

Location

United States

Related Subject Headings

  • Therapeutic Irrigation
  • Pulmonary Alveoli
  • Pneumonia, Pneumocystis
  • Pathology
  • Opportunistic Infections
  • Middle Aged
  • Male
  • Lung
  • Humans
  • Histocytochemistry