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The acquired immunodeficiency syndrome in intravenous drug abusers and patients with a sexual risk: clinical and postmortem comparisons.

Publication ,  Journal Article
Ambros, RA; Lee, EY; Sharer, LR; Khan, MY; Robboy, SJ
Published in: Hum Pathol
November 1987

Clinical and necropsy findings in 13 intravenous drug abusers who died of the acquired immunodeficiency syndrome (AIDS) were reviewed and compared with findings in eight patients who acquired the infection through sexual exposure, the most common mode of transmission in AIDS. No differences were found in lymphocyte counts or duration of survival, despite reports that the degree of immunosuppression in intravenous drug abusers with AIDS differs from that in homosexuals. Neoplasms were found in 25 per cent of patients with sexual risks, but not in any drug abusers (0 per cent). Two opportunistic infections (toxoplasmosis and cytomegalovirus pneumonia and esophagitis) were more common in the intravenous drug abuser group. Although cytomegalovirus has been associated with Kaposi's sarcoma, this association was not found in this study. The postmortem findings in both groups were otherwise similar.

Duke Scholars

Published In

Hum Pathol

DOI

ISSN

0046-8177

Publication Date

November 1987

Volume

18

Issue

11

Start / End Page

1109 / 1114

Location

United States

Related Subject Headings

  • Toxoplasmosis
  • Substance-Related Disorders
  • Risk Factors
  • Pneumonia, Pneumocystis
  • Pathology
  • Opportunistic Infections
  • Neoplasms
  • Male
  • Lymph Nodes
  • Leukocyte Count
 

Citation

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Ambros, R. A., Lee, E. Y., Sharer, L. R., Khan, M. Y., & Robboy, S. J. (1987). The acquired immunodeficiency syndrome in intravenous drug abusers and patients with a sexual risk: clinical and postmortem comparisons. Hum Pathol, 18(11), 1109–1114. https://doi.org/10.1016/s0046-8177(87)80377-5
Ambros, R. A., E. Y. Lee, L. R. Sharer, M. Y. Khan, and S. J. Robboy. “The acquired immunodeficiency syndrome in intravenous drug abusers and patients with a sexual risk: clinical and postmortem comparisons.Hum Pathol 18, no. 11 (November 1987): 1109–14. https://doi.org/10.1016/s0046-8177(87)80377-5.
Ambros, R. A., et al. “The acquired immunodeficiency syndrome in intravenous drug abusers and patients with a sexual risk: clinical and postmortem comparisons.Hum Pathol, vol. 18, no. 11, Nov. 1987, pp. 1109–14. Pubmed, doi:10.1016/s0046-8177(87)80377-5.
Ambros RA, Lee EY, Sharer LR, Khan MY, Robboy SJ. The acquired immunodeficiency syndrome in intravenous drug abusers and patients with a sexual risk: clinical and postmortem comparisons. Hum Pathol. 1987 Nov;18(11):1109–1114.
Journal cover image

Published In

Hum Pathol

DOI

ISSN

0046-8177

Publication Date

November 1987

Volume

18

Issue

11

Start / End Page

1109 / 1114

Location

United States

Related Subject Headings

  • Toxoplasmosis
  • Substance-Related Disorders
  • Risk Factors
  • Pneumonia, Pneumocystis
  • Pathology
  • Opportunistic Infections
  • Neoplasms
  • Male
  • Lymph Nodes
  • Leukocyte Count