Silent corticotroph cell pituitary adenoma in a struma ovarii.

Journal Article (Journal Article)

This is the first report of a silent corticotroph cell pituitary adenoma arising in a struma ovarii. The patient, a 79-year-old woman, was found to have an asymptomatic left-sided adnexal mass confirmed by vaginal sonography to be a complex cystic and solid tumor. Pathological analysis demonstrated an 8-cm partially cystic struma ovarii in which there was a focus of predominantly basophilic adenohypophyseal cells arranged in a diffuse pattern, adjacent to mature neural tissue containing numerous Herring bodies. The epithelial lining cells of the colloid-filled small and cystic follicles were immunoreactive for thyroglobulin. The pituitary cells were predominantly immunoreactive for adrenocorticotropic hormone, in addition to synaptophysin.

Full Text

Duke Authors

Cited Authors

  • Waugh, MS; Soler, AP; Robboy, SJ

Published Date

  • January 1, 2007

Published In

Volume / Issue

  • 26 / 1

Start / End Page

  • 26 - 29

PubMed ID

  • 17197893

International Standard Serial Number (ISSN)

  • 0277-1691

Digital Object Identifier (DOI)

  • 10.1097/01.pgp.0000228139.94339.e0


  • eng

Conference Location

  • United States