Carcinoma of the esophagus with mixed basaloid squamous and glandular differentiation: a distinct histological presentation.

Journal Article

Esophageal cancer is the third most common gastrointestinal cancer and ranks among the ten commonest cancers worldwide. Histologically, approx 60% of esophageal cancers are adenocarcinomas and 40% are squamous cell carcinomas (SCC). Other rare cancers of the esophagus include small-cell carcinomas, squamous cell carcinomas with sarcomatous features, adenoid cystic carcinomas, and mucoepidermoid carcinomas. Basaloid squamous cell carcinoma (BSCC) or basaloid squamous carcinoma (BSC) is a distinct clinicopathological entity, seen more frequently in elderly males. Stage at presentation is often advanced and regional adenopathy or distant metastases are not uncommon at presentation. We describe an unusual case report of esophageal BSCC with glandular differentiation. The clinical significance of glandular differentiation in this rare type of tumor is not known.

Full Text

Duke Authors

Cited Authors

  • Bhagat, V; Javle, M; Geradts, J

Published Date

  • 2003

Published In

Volume / Issue

  • 34 / 2-3

Start / End Page

  • 139 - 142

PubMed ID

  • 15361648

Pubmed Central ID

  • 15361648

International Standard Serial Number (ISSN)

  • 1537-3649

Digital Object Identifier (DOI)

  • 10.1385/IJGC:34:2-3:139


  • eng

Conference Location

  • United States