Human breast cancer specimens: diffraction-enhanced imaging with histologic correlation--improved conspicuity of lesion detail compared with digital radiography.

Journal Article (Journal Article)

Seven breast cancer specimens were examined with diffraction-enhanced imaging at 18 keV with a silicon crystal with use of the silicon 333 reflection in Bragg mode. Images were compared with digital radiographs of the specimen, and regions of increased detail were identified. Six of the seven cases (86%) showed enhanced visibility of surface spiculation that correlated with histopathologic information, including extension of tumor into surrounding tissue.

Full Text

Duke Authors

Cited Authors

  • Pisano, ED; Johnston, RE; Chapman, D; Geradts, J; Iacocca, MV; Livasy, CA; Washburn, DB; Sayers, DE; Zhong, Z; Kiss, MZ; Thomlinson, WC

Published Date

  • March 2000

Published In

Volume / Issue

  • 214 / 3

Start / End Page

  • 895 - 901

PubMed ID

  • 10715065

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.214.3.r00mr26895


  • eng

Conference Location

  • United States