Secure analysis of distributed chemical databases without data integration.
Publication
, Journal Article
Karr, AF; Feng, J; Lin, X; Sanil, AP; Young, SS; Reiter, JP
Published in: Journal of computer-aided molecular design
September 2005
We present a method for performing statistically valid linear regressions on the union of distributed chemical databases that preserves confidentiality of those databases. The method employs secure multi-party computation to share local sufficient statistics necessary to compute least squares estimators of regression coefficients, error variances and other quantities of interest. We illustrate our method with an example containing four companies' rather different databases.
Duke Scholars
Published In
Journal of computer-aided molecular design
DOI
EISSN
1573-4951
ISSN
0920-654X
Publication Date
September 2005
Volume
19
Issue
9-10
Start / End Page
739 / 747
Related Subject Headings
- Water
- Solubility
- Regression Analysis
- Organic Chemicals
- Models, Chemical
- Medicinal & Biomolecular Chemistry
- Linear Models
- Least-Squares Analysis
- Databases, Factual
- Computer Security
Citation
APA
Chicago
ICMJE
MLA
NLM
Karr, A. F., Feng, J., Lin, X., Sanil, A. P., Young, S. S., & Reiter, J. P. (2005). Secure analysis of distributed chemical databases without data integration. Journal of Computer-Aided Molecular Design, 19(9–10), 739–747. https://doi.org/10.1007/s10822-005-9011-5
Karr, Alan F., Jun Feng, Xiaodong Lin, Ashish P. Sanil, S Stanley Young, and Jerome P. Reiter. “Secure analysis of distributed chemical databases without data integration.” Journal of Computer-Aided Molecular Design 19, no. 9–10 (September 2005): 739–47. https://doi.org/10.1007/s10822-005-9011-5.
Karr AF, Feng J, Lin X, Sanil AP, Young SS, Reiter JP. Secure analysis of distributed chemical databases without data integration. Journal of computer-aided molecular design. 2005 Sep;19(9–10):739–47.
Karr, Alan F., et al. “Secure analysis of distributed chemical databases without data integration.” Journal of Computer-Aided Molecular Design, vol. 19, no. 9–10, Sept. 2005, pp. 739–47. Epmc, doi:10.1007/s10822-005-9011-5.
Karr AF, Feng J, Lin X, Sanil AP, Young SS, Reiter JP. Secure analysis of distributed chemical databases without data integration. Journal of computer-aided molecular design. 2005 Sep;19(9–10):739–747.
Published In
Journal of computer-aided molecular design
DOI
EISSN
1573-4951
ISSN
0920-654X
Publication Date
September 2005
Volume
19
Issue
9-10
Start / End Page
739 / 747
Related Subject Headings
- Water
- Solubility
- Regression Analysis
- Organic Chemicals
- Models, Chemical
- Medicinal & Biomolecular Chemistry
- Linear Models
- Least-Squares Analysis
- Databases, Factual
- Computer Security