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Pediatric cardiac-gated CT angiography: assessment of radiation dose.

Publication ,  Journal Article
Hollingsworth, CL; Yoshizumi, TT; Frush, DP; Chan, FP; Toncheva, G; Nguyen, G; Lowry, CR; Hurwitz, LM
Published in: AJR Am J Roentgenol
July 2007

OBJECTIVE: The purpose of our study was to determine a dose range for cardiac-gated CT angiography (CTA) in children. MATERIALS AND METHODS: ECG-gated cardiac CTA simulating scanning of the heart was performed on an anthropomorphic phantom of a 5-year-old child on a 16-MDCT scanner using variable parameters (small field of view; 16 x 0.625 mm configuration; 0.5-second gantry cycle time; 0.275 pitch; 120 kVp at 110, 220, and 330 mA; and 80 kVp at 385 mA). Metal oxide semiconductor field effect transistor (MOSFET) technology measured 20 organ doses. Effective dose calculated using the dose-length product (DLP) was compared with effective dose determined from measured absorbed organ doses. RESULTS: Highest organ doses included breast (3.5-12.6 cGy), lung (3.3-12.1 cGy), and bone marrow (1.7-7.6 cGy). The 80 kVp/385 mA examination produced lower radiation doses to all organs than the 120 kVp/220 mA examination. MOSFET effective doses (+/- SD) were as follows: 110 mA: 7.4 mSv (+/- 0.6 mSv), 220 mA: 17.2 mSv (+/- 0.3 mSv), 330 mA: 25.7 mSv (+/- 0.3 mSv), 80 kVp/385 mA: 10.6 mSv (+/- 0.2 mSv). DLP effective doses for diagnostic runs were as follows: 110 mA: 8.7 mSv, 220 mA: 19 mSv, 330 mA: 28 mSv, 80 kVp/385 mA: 12 mSv. DLP effective doses exceeded MOSFET effective doses by 9.7-17.2%. CONCLUSION: Radiation doses for a 5-year-old during cardiac-gated CTA vary greatly depending on parameters. Organ doses can be high; the effective dose may reach 28.4 mSv. Further work, including determination of size-appropriate mA and image quality, is important before routine use of this technique in children.

Duke Scholars

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

July 2007

Volume

189

Issue

1

Start / End Page

12 / 18

Location

United States

Related Subject Headings

  • Whole-Body Counting
  • Tomography, X-Ray Computed
  • Risk Assessment
  • Relative Biological Effectiveness
  • Radiometry
  • Radiation Protection
  • Radiation Dosage
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Electrocardiography
 

Citation

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Hollingsworth, C. L., Yoshizumi, T. T., Frush, D. P., Chan, F. P., Toncheva, G., Nguyen, G., … Hurwitz, L. M. (2007). Pediatric cardiac-gated CT angiography: assessment of radiation dose. AJR Am J Roentgenol, 189(1), 12–18. https://doi.org/10.2214/AJR.06.1507
Hollingsworth, Caroline L., Terry T. Yoshizumi, Donald P. Frush, Frandics P. Chan, Greta Toncheva, Giao Nguyen, Carolyn R. Lowry, and Lynne M. Hurwitz. “Pediatric cardiac-gated CT angiography: assessment of radiation dose.AJR Am J Roentgenol 189, no. 1 (July 2007): 12–18. https://doi.org/10.2214/AJR.06.1507.
Hollingsworth CL, Yoshizumi TT, Frush DP, Chan FP, Toncheva G, Nguyen G, et al. Pediatric cardiac-gated CT angiography: assessment of radiation dose. AJR Am J Roentgenol. 2007 Jul;189(1):12–8.
Hollingsworth, Caroline L., et al. “Pediatric cardiac-gated CT angiography: assessment of radiation dose.AJR Am J Roentgenol, vol. 189, no. 1, July 2007, pp. 12–18. Pubmed, doi:10.2214/AJR.06.1507.
Hollingsworth CL, Yoshizumi TT, Frush DP, Chan FP, Toncheva G, Nguyen G, Lowry CR, Hurwitz LM. Pediatric cardiac-gated CT angiography: assessment of radiation dose. AJR Am J Roentgenol. 2007 Jul;189(1):12–18.

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

July 2007

Volume

189

Issue

1

Start / End Page

12 / 18

Location

United States

Related Subject Headings

  • Whole-Body Counting
  • Tomography, X-Ray Computed
  • Risk Assessment
  • Relative Biological Effectiveness
  • Radiometry
  • Radiation Protection
  • Radiation Dosage
  • Nuclear Medicine & Medical Imaging
  • Humans
  • Electrocardiography