Adjuvant chemotherapy in primary treatment of osteogenic sarcoma. A Southwest Oncology Group study.

Journal Article (Journal Article)

A four-drug adjuvant chemotherapy regimen (CONPADRI-I) was utilized in the primary treatment of 18 children with osteogenic sarcoma. All patients had surgical amputation for the primary lesion. The children then received cyclophosphamide, vincristine, melphalan, and adriamycin in defined combinations intermittently over a 72-week period. Of the 18 patients, 10 (55%) remain free of disease 24 months or longer from time of amputation.

Full Text

Duke Authors

Cited Authors

  • Sutow, WW; Sullivan, MP; Fernbach, DJ; Cangir, A; George, SL

Published Date

  • November 1, 1975

Published In

Volume / Issue

  • 36 / 5

Start / End Page

  • 1598 - 1602

PubMed ID

  • 1059501

International Standard Serial Number (ISSN)

  • 0008-543X

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(197511)36:5<1598::aid-cncr2820360511>;2-n


  • eng

Conference Location

  • United States