Nonocclusion and spontaneous recanalization rates in acute ischemic stroke: a review of cerebral angiography studies.


Journal Article (Review)

BACKGROUND: Spontaneous recanalization is an understudied phenomenon in stroke. It is often overestimated by nonocclusion rates. The heterogeneity of the causes and manifestations of stroke and of the studies assessing vascular patency has created difficulties in assigning accurate rates of its incidence. METHODS: Systematic review of published articles about cerebral angiography in stroke. RESULTS: Lack of anticipated occlusions (nonocclusion rates) was noted in 28% of patients in suspected vessels 6 hours after stroke onset, whereas documented occlusions were noted in 17% of patients who underwent spontaneous lysis at 6 to 8 hours. At 3 to 4 days, the nonocclusion rate was 50% of studied vessels. CONCLUSIONS: In the first 6 to 8 hours from stroke onset, spontaneous recanalization occurs in approximately 17% of patients, whereas nonocclusion exists in about 28% of patients and up to 50% by 4 days after stroke.

Full Text

Duke Authors

Cited Authors

  • Kassem-Moussa, H; Graffagnino, C

Published Date

  • December 2002

Published In

Volume / Issue

  • 59 / 12

Start / End Page

  • 1870 - 1873

PubMed ID

  • 12470173

Pubmed Central ID

  • 12470173

International Standard Serial Number (ISSN)

  • 0003-9942

Digital Object Identifier (DOI)

  • 10.1001/archneur.59.12.1870


  • eng

Conference Location

  • United States