A practical approach for comparing means of two groups without equal variance assumption.
Publication
, Journal Article
Wang, H; Chow, S-C
Published in: Stat Med
October 30, 2002
In this paper we consider two-groups of i.i.d. normally distributed random variables (N(mu(x),sigma(x) (2)) and N(mu(y),sigma(y) (2))) without assuming equal variance (sigma(x) (2) = sigma(y) (2)). We propose a simple method for constructing confidence bounds based on Howe's approximation I. Its applications in parallel clinical trial (testing H(0) : mu(x)-mu(y)=0 versus H(1) : mu(x)-mu(y)<0) and parallel bioequivalence (BE) trial (testing H(0):mid R:mu(x)-mu(y)mid R:delta versus H(1):mid R:mu(x)-mu(y)mid R:
Duke Scholars
Published In
Stat Med
DOI
ISSN
0277-6715
Publication Date
October 30, 2002
Volume
21
Issue
20
Start / End Page
3137 / 3151
Location
England
Related Subject Headings
- Therapeutic Equivalency
- Statistics as Topic
- Statistics & Probability
- Sample Size
- Humans
- Confidence Intervals
- Clinical Trials as Topic
- Analysis of Variance
- 4905 Statistics
- 4202 Epidemiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Wang, H., & Chow, S.-C. (2002). A practical approach for comparing means of two groups without equal variance assumption. Stat Med, 21(20), 3137–3151. https://doi.org/10.1002/sim.1238
Wang, Hansheng, and Shein-Chung Chow. “A practical approach for comparing means of two groups without equal variance assumption.” Stat Med 21, no. 20 (October 30, 2002): 3137–51. https://doi.org/10.1002/sim.1238.
Wang H, Chow S-C. A practical approach for comparing means of two groups without equal variance assumption. Stat Med. 2002 Oct 30;21(20):3137–51.
Wang, Hansheng, and Shein-Chung Chow. “A practical approach for comparing means of two groups without equal variance assumption.” Stat Med, vol. 21, no. 20, Oct. 2002, pp. 3137–51. Pubmed, doi:10.1002/sim.1238.
Wang H, Chow S-C. A practical approach for comparing means of two groups without equal variance assumption. Stat Med. 2002 Oct 30;21(20):3137–3151.
Published In
Stat Med
DOI
ISSN
0277-6715
Publication Date
October 30, 2002
Volume
21
Issue
20
Start / End Page
3137 / 3151
Location
England
Related Subject Headings
- Therapeutic Equivalency
- Statistics as Topic
- Statistics & Probability
- Sample Size
- Humans
- Confidence Intervals
- Clinical Trials as Topic
- Analysis of Variance
- 4905 Statistics
- 4202 Epidemiology