Co-existence of chronic fatigue syndrome with fibromyalgia syndrome in the general population. A controlled study.

Journal Article (Journal Article)

OBJECTIVE: To determine the proportion of adults with fibromyalgia syndrome (FMS) in the general population who also meet the 1988 Centre for Disease Control (CDC) criteria for chronic fatigue syndrome (CFS). METHODS: Seventy-four FMS cases were compared with 32 non-FMS controls with widespread pain and 23 with localized pain, all recruited in a general population survey. RESULTS: Among females, 58.0% of fibromyalgia cases met the full criteria for CFS, compared to 26.1% and 12.5% of controls with widespread and localized pain, respectively (p=0.0006). Male percentages were 80.0, 22.2, and zero, respectively (p=0.003). Compared to those with FMS alone, those meeting the case definitions for both FMS and CFS reported a worse course, worse overall health, more dissatisfaction with health, more non-CFS symptoms, and greater disease impact. The number of total symptoms and non-CFS symptoms were the best predictors of co-morbid CFS. CONCLUSIONS: There is significant clinical overlap between CFS and FMS.

Full Text

Duke Authors

Cited Authors

  • White, KP; Speechley, M; Harth, M; Ostbye, T

Published Date

  • 2000

Published In

Volume / Issue

  • 29 / 1

Start / End Page

  • 44 - 51

PubMed ID

  • 10722257

International Standard Serial Number (ISSN)

  • 0300-9742

Digital Object Identifier (DOI)

  • 10.1080/030097400750001798


  • eng

Conference Location

  • England