Critical review: nicotine for the fetus, the infant and the adolescent?

Journal Article (Journal Article;Review)

The recent expansion of Nicotine Replacement Therapy to pregnant women and children ignores the fact that nicotine impairs, disrupts, duplicates and/or interacts with essential physiological functions and is involved in tobacco-related carcinogenesis. The main concerns in the present context are its fetotoxicity and neuroteratogenicity that can cause cognitive, affective and behavioral disorders in children born to mothers exposed to nicotine during pregnancy, and the detrimental effects of nicotine on the growing organism. Hence, the use of nicotine, whose efficacy in treating nicotine addiction is controversial even in adults, must be strictly avoided in pregnancy, breastfeeding, childhood and adolescence.

Full Text

Duke Authors

Cited Authors

  • Ginzel, KH; Maritz, GS; Marks, DF; Neuberger, M; Pauly, JR; Polito, JR; Schulte-Hermann, R; Slotkin, TA

Published Date

  • March 2007

Published In

Volume / Issue

  • 12 / 2

Start / End Page

  • 215 - 224

PubMed ID

  • 17284486

International Standard Serial Number (ISSN)

  • 1359-1053

Digital Object Identifier (DOI)

  • 10.1177/1359105307074240


  • eng

Conference Location

  • England