Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke.


Journal Article

The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual recognition memory and auditory function (auditory brainstem response). The ETS group showed significantly less novelty preference in the visual recognition task whereas no effects on auditory function were detected. These preliminary results support the view that perinatal ETS exposure has adverse effects on cognitive function and indicate further that rhesus monkeys may provide a valuable nonhuman primate model for investigating this link.

Full Text

Duke Authors

Cited Authors

  • Golub, MS; Slotkin, TA; Tarantal, AF; Pinkerton, KE

Published Date

  • June 2, 2007

Published In

Volume / Issue

  • 1151 /

Start / End Page

  • 102 - 106

PubMed ID

  • 17399690

Pubmed Central ID

  • 17399690

International Standard Serial Number (ISSN)

  • 0006-8993

Digital Object Identifier (DOI)

  • 10.1016/j.brainres.2007.03.001


  • eng

Conference Location

  • Netherlands