An involvement of dopamine in higher order choice mechanisms in the monkey.

Journal Article

Low doses of amphetamine induce choice perseveration in an object discrimination task under conditions where such perseveration either increases or decreases the number of rewards obtained as compared to chance performance. Neither stereotyped motor actions nor repetitive choice of position contributed to this effect which could be blocked by pre-treatment with the neuroleptic haloperidol. These results demonstrate that higher order choice mechanisms may involve dopamine systems in the primate.

Full Text

Duke Authors

Cited Authors

  • Ridley, RM; Haystead, TA; Baker, HF

Published Date

  • 1981

Published In

Volume / Issue

  • 72 / 2

Start / End Page

  • 173 - 177

PubMed ID

  • 6782607

International Standard Serial Number (ISSN)

  • 0033-3158

Language

  • eng

Conference Location

  • Germany