Phosphorylation of caldesmon by mitogen-activated protein kinase with no effect on Ca2+ sensitivity in rabbit smooth muscle.
Journal Article (Journal Article)
1. Recombinant, activated mitogen-activated protein kinase (3.3 microM; p42mapk) phosphorylated caldesmon in phasic (rabbit portal vein) and tonic (rabbit femoral artery) smooth muscle strips permeabilized with Triton X-100. 2. Phosphorylation of caldesmon by p42mapk neither induced contraction of relaxed smooth muscle nor affected the Ca2+ sensitivity of submaximally contracted permeabilized phasic or tonic smooth muscle.
- Nixon, GF; Iizuka, K; Haystead, CM; Haystead, TA; Somlyo, AP; Somlyo, AV
- September 1, 1995
Volume / Issue
- 487 ( Pt 2) / Pt 2
Start / End Page
- 283 - 289
Pubmed Central ID
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)