A new approach to the role of noradrenaline in learning: problem-solving in the marmoset after alpha-noradrenergic receptor blockade.

Journal Article (Journal Article)

Nine marmosets (Callithrix jacchus) were tested on a variety of visual discrimination learning tasks in a Wisconsin General Test Apparatus with or without alpha-noradrenergic receptor blockade achieved by the administration of aceperone. After aceperone, animals were found to be severely and consistently impaired at learning the first task of each test session and to be impaired on new and repeated reversal learning. They were, however, unimpaired on learning another similar task in each test session and on performance of a well-learnt task. Results were interpreted as evidence for defective association formation which can be compensated for by suitable priming or practice.

Full Text

Duke Authors

Cited Authors

  • Ridley, RM; Haystead, TA; Baker, HF; Crow, TJ

Published Date

  • June 1981

Published In

Volume / Issue

  • 14 / 6

Start / End Page

  • 849 - 855

PubMed ID

  • 6114497

International Standard Serial Number (ISSN)

  • 0091-3057

Digital Object Identifier (DOI)

  • 10.1016/0091-3057(81)90373-7


  • eng

Conference Location

  • United States