Amyloid myopathy presenting with respiratory failure.


Journal Article

Amyloidosis is a rare cause of myopathy. Its prominent or presenting feature may be respiratory failure. Physiological measurement of transdiaphragmatic pressure and biopsy specimens of muscle show the pathological mechanism to be diaphragm weakness due to amyloid infiltration of the diaphragm rather than parenchymal lung involvement. Thus amyloid myopathy even without the typical macroglossia and muscle pseudohypertrophy should be considered as one of the neurological causes of respiratory failure.

Full Text

Duke Authors

Cited Authors

  • Ashe, J; Borel, CO; Hart, G; Humphrey, RL; Derrick, DA; Kuncl, RW

Published Date

  • February 1, 1992

Published In

Volume / Issue

  • 55 / 2

Start / End Page

  • 162 - 165

PubMed ID

  • 1538226

Pubmed Central ID

  • 1538226

International Standard Serial Number (ISSN)

  • 0022-3050

Digital Object Identifier (DOI)

  • 10.1136/jnnp.55.2.162


  • eng

Conference Location

  • England