Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16.
Publication
, Journal Article
Bateman, JB; Klisak, I; Kojis, T; Mohandas, T; Sparkes, RS; Li, TS; Applebury, ML; Bowes, C; Farber, DB
Published in: Genomics
March 1992
The gene encoding the beta-subunit of rod photoreceptor cGMP phosphodiesterase (gene symbol PDEB, homolog of the mouse rd gene) is mapped to human chromosome 4 using somatic cell hybrids and further localized to the chromosome band 4p16 using in situ hybridization. A mutation in the mouse gene underlies the recessive trait of retinal degeneration in the rd mouse. Thus, the human homolog is a candidate for lesions causing retinal degeneration.
Duke Scholars
Published In
Genomics
DOI
ISSN
0888-7543
Publication Date
March 1992
Volume
12
Issue
3
Start / End Page
601 / 603
Location
United States
Related Subject Headings
- Photoreceptor Cells
- Mice
- Macromolecular Substances
- Hybrid Cells
- Humans
- Genetics & Heredity
- Chromosomes, Human, Pair 4
- Chromosome Banding
- Biological Evolution
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Bateman, J. B., Klisak, I., Kojis, T., Mohandas, T., Sparkes, R. S., Li, T. S., … Farber, D. B. (1992). Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16. Genomics, 12(3), 601–603. https://doi.org/10.1016/0888-7543(92)90454-z
Bateman, J. B., I. Klisak, T. Kojis, T. Mohandas, R. S. Sparkes, T. S. Li, M. L. Applebury, C. Bowes, and D. B. Farber. “Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16.” Genomics 12, no. 3 (March 1992): 601–3. https://doi.org/10.1016/0888-7543(92)90454-z.
Bateman JB, Klisak I, Kojis T, Mohandas T, Sparkes RS, Li TS, et al. Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16. Genomics. 1992 Mar;12(3):601–3.
Bateman, J. B., et al. “Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16.” Genomics, vol. 12, no. 3, Mar. 1992, pp. 601–03. Pubmed, doi:10.1016/0888-7543(92)90454-z.
Bateman JB, Klisak I, Kojis T, Mohandas T, Sparkes RS, Li TS, Applebury ML, Bowes C, Farber DB. Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16. Genomics. 1992 Mar;12(3):601–603.
Published In
Genomics
DOI
ISSN
0888-7543
Publication Date
March 1992
Volume
12
Issue
3
Start / End Page
601 / 603
Location
United States
Related Subject Headings
- Photoreceptor Cells
- Mice
- Macromolecular Substances
- Hybrid Cells
- Humans
- Genetics & Heredity
- Chromosomes, Human, Pair 4
- Chromosome Banding
- Biological Evolution
- Animals