Post-translational modifications regulate the ticking of the circadian clock.
Publication
, Journal Article
Gallego, M; Virshup, DM
Published in: Nat Rev Mol Cell Biol
February 2007
Getting a good night's sleep is on everyone's to-do list. So is, no doubt, staying awake during late afternoon seminars. Our internal clocks control these and many more workings of the body, and disruptions of the circadian clocks predispose individuals to depression, obesity and cancer. Mutations in kinases and phosphatases in hamsters, flies, fungi and humans highlight how our timepieces are regulated and provide clues as to how we might be able to manipulate them.
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Published In
Nat Rev Mol Cell Biol
DOI
ISSN
1471-0072
Publication Date
February 2007
Volume
8
Issue
2
Start / End Page
139 / 148
Location
England
Related Subject Headings
- Signal Transduction
- Protein Processing, Post-Translational
- Phosphotransferases
- Phosphorylation
- Phosphoric Monoester Hydrolases
- Neurospora crassa
- Humans
- Gene Expression Regulation
- Feedback, Physiological
- Drosophila melanogaster
Citation
APA
Chicago
ICMJE
MLA
NLM
Gallego, M., & Virshup, D. M. (2007). Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cell Biol, 8(2), 139–148. https://doi.org/10.1038/nrm2106
Gallego, Monica, and David M. Virshup. “Post-translational modifications regulate the ticking of the circadian clock.” Nat Rev Mol Cell Biol 8, no. 2 (February 2007): 139–48. https://doi.org/10.1038/nrm2106.
Gallego M, Virshup DM. Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cell Biol. 2007 Feb;8(2):139–48.
Gallego, Monica, and David M. Virshup. “Post-translational modifications regulate the ticking of the circadian clock.” Nat Rev Mol Cell Biol, vol. 8, no. 2, Feb. 2007, pp. 139–48. Pubmed, doi:10.1038/nrm2106.
Gallego M, Virshup DM. Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cell Biol. 2007 Feb;8(2):139–148.
Published In
Nat Rev Mol Cell Biol
DOI
ISSN
1471-0072
Publication Date
February 2007
Volume
8
Issue
2
Start / End Page
139 / 148
Location
England
Related Subject Headings
- Signal Transduction
- Protein Processing, Post-Translational
- Phosphotransferases
- Phosphorylation
- Phosphoric Monoester Hydrolases
- Neurospora crassa
- Humans
- Gene Expression Regulation
- Feedback, Physiological
- Drosophila melanogaster