ZEITLUPE encodes a novel clock-associated PAS protein from Arabidopsis.

Published

Journal Article

We have conducted genetic screens for period length mutants in Arabidopsis using a transgenic bioluminescence phenotype. This screen identified mutations at a locus, ZEITLUPE (ZTL), that lengthen the free-running period of clock-controlled gene transcription and cell expansion, and alter the timing of the daylength-dependent transition from vegetative to floral development. Map-based cloning of ZTL identified a novel 609 amino acid polypeptide consisting of an amino-terminal PAS domain, an F box and six carboxy-terminal kelch repeats. The PAS region is highly similar to the PAS domain of the Arabidopsis blue-light receptor NPH1, and the Neurospora circadian-associated protein WHITE COLLAR-1 (WC-1). The striking fluence rate-dependent effect of the ztl mutations suggests that ZTL plays a primary role in the photocontrol of circadian period in higher plants.

Full Text

Duke Authors

Cited Authors

  • Somers, DE; Schultz, TF; Milnamow, M; Kay, SA

Published Date

  • April 2000

Published In

Volume / Issue

  • 101 / 3

Start / End Page

  • 319 - 329

PubMed ID

  • 10847686

Pubmed Central ID

  • 10847686

Electronic International Standard Serial Number (EISSN)

  • 1097-4172

International Standard Serial Number (ISSN)

  • 0092-8674

Digital Object Identifier (DOI)

  • 10.1016/s0092-8674(00)80841-7

Language

  • eng