Caffeine raises blood pressure at work.

Journal Article (Clinical Trial;Journal Article)

OBJECTIVE: The study investigated the effects of moderate doses of caffeine on ambulatory blood pressure and heart rate during workday activities. METHODS: Healthy, nonsmoking, habitual coffee drinkers (N = 21) received daily doses of 100 mg and 500 mg of caffeine on 2 days in a crossover design. Treatment order was random and counterbalanced, and administration was double-blind. Ambulatory monitoring was conducted for 6 to 9 hours during normal workday activities and diary entries were completed at each measurement. Ambulatory data were analyzed for the effects of caffeine dose, controlling for variations in posture, physical activity, and perceived stress. RESULTS: The average workday blood pressure and heart rate were significantly higher when the higher dose of caffeine was consumed. Controlling for other factors, dose-related differences were 4 mm Hg for systolic and 3 mm Hg for diastolic blood pressure, and were 3 bpm for heart rate. CONCLUSIONS: Results support earlier evidence that caffeine raises blood pressure at work, and demonstrate that these pressor effects are independent of changes in posture, physical activity, or stress. Daily blood pressure increases associated with caffeine consumption could increase the risk of developing cardiovascular diseases. In addition, caffeine consumption effects might confound ambulatory investigations of the cardiovascular effects of other psychosocial, personality, or health-behavior factors.

Full Text

Duke Authors

Cited Authors

  • Lane, JD; Phillips-Bute, BG; Pieper, CF

Published Date

  • May 1998

Published In

Volume / Issue

  • 60 / 3

Start / End Page

  • 327 - 330

PubMed ID

  • 9625220

International Standard Serial Number (ISSN)

  • 0033-3174

Digital Object Identifier (DOI)

  • 10.1097/00006842-199805000-00019


  • eng

Conference Location

  • United States