Imaging of the human heart after administration of L-(N-13)glutamate.

Journal Article

In normal volunteers and cancer patients, studies using L-(N-13)glutamate as an imaging agent showed localization of N-13 activity in the heart. Other organs that were well visualized include the liver, pancreas, and salivary glands. In ten subjects the average myocardial uptake after intravenous injection of labeled glutamate was (5.7 +/- 0.39)% (s.e.m.) of injected dose, as determined by a quantitative scanning system. The concentration of N-13 activity in the human heart could not be predicted from previous studies involving myocardial uptake in dogs and rodents after administration of L-(N-13)glutamate.

Full Text

Duke Authors

Cited Authors

  • Gelbard, AS; Benua, RS; Reiman, RE; McDonald, JM; Vomero, JJ; Laughlin, JS

Published Date

  • October 1, 1980

Published In

Volume / Issue

  • 21 / 10

Start / End Page

  • 988 - 991

PubMed ID

  • 7420199

International Standard Serial Number (ISSN)

  • 0161-5505

Language

  • eng

Conference Location

  • United States