Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication.
Publication
, Journal Article
Reiman, RE; Benua, RS; Gelbard, AS; Allen, JC; Vomero, JJ; Laughlin, JS
Published in: J Nucl Med
August 1982
Cyclotron-produced L-(N-13)glutamate was used to visualize malignant intracranial tumors in 12 pediatric patients who had evidence of recurrent disease as documented by computed transaxial tomography (TCT). Imaging was performed using a rectilinear scanner, gamma camera, or a positron-emission tomograph (PET). The results indicate that N-13 is rapidly taken up by a majority of brain tumors following the administration of L-(N-13)glutamate, and that N-13 uptake is correlated with breakdown of the blood-brain barrier as demonstrated by contrast TCT or pertechnetate (Tc-99m) studies. The feasibility of using this agent in conjunction with PET is established.
Duke Scholars
Published In
J Nucl Med
ISSN
0161-5505
Publication Date
August 1982
Volume
23
Issue
8
Start / End Page
682 / 687
Location
United States
Related Subject Headings
- Tomography, X-Ray Computed
- Tomography, Emission-Computed
- Technetium
- Sodium Pertechnetate Tc 99m
- Nuclear Medicine & Medical Imaging
- Nitrogen Radioisotopes
- Male
- Humans
- Glutamic Acid
- Glutamates
Citation
APA
Chicago
ICMJE
MLA
NLM
Reiman, R. E., Benua, R. S., Gelbard, A. S., Allen, J. C., Vomero, J. J., & Laughlin, J. S. (1982). Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication. J Nucl Med, 23(8), 682–687.
Reiman, R. E., R. S. Benua, A. S. Gelbard, J. C. Allen, J. J. Vomero, and J. S. Laughlin. “Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication.” J Nucl Med 23, no. 8 (August 1982): 682–87.
Reiman RE, Benua RS, Gelbard AS, Allen JC, Vomero JJ, Laughlin JS. Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication. J Nucl Med. 1982 Aug;23(8):682–7.
Reiman, R. E., et al. “Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication.” J Nucl Med, vol. 23, no. 8, Aug. 1982, pp. 682–87.
Reiman RE, Benua RS, Gelbard AS, Allen JC, Vomero JJ, Laughlin JS. Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication. J Nucl Med. 1982 Aug;23(8):682–687.
Published In
J Nucl Med
ISSN
0161-5505
Publication Date
August 1982
Volume
23
Issue
8
Start / End Page
682 / 687
Location
United States
Related Subject Headings
- Tomography, X-Ray Computed
- Tomography, Emission-Computed
- Technetium
- Sodium Pertechnetate Tc 99m
- Nuclear Medicine & Medical Imaging
- Nitrogen Radioisotopes
- Male
- Humans
- Glutamic Acid
- Glutamates