Quantitative scanning of osteogenic sarcoma with nitrogen-13-labeled L-glutamate.

Journal Article (Journal Article)

N-13 L-glutamate was used to image an osteogenic sarcoma in a 9-year-old patient. Serial quantitative measurements of the amount of N-13 taken up by the primary tumor showed a decrease of 40% after 10 wk of chemotherapy. Blood-clearance data obtained from normal subjects indicate that more than 90% of the N-13 activity had left the blood before scanning of the tumor was begun. It appears that the N-13 label concentrated in the soft-tissue portion of this osteogenic sarcoma, whereas Tc-99m diphosphonate uptake was greatest in the regions where calcification was occurring.

Full Text

Duke Authors

Cited Authors

  • Gelbard, AS; Benua, RS; Laughlin, JS; Rosen, G; Reiman, RE; McDonald, JM

Published Date

  • July 1, 1979

Published In

Volume / Issue

  • 20 / 7

Start / End Page

  • 782 - 784

PubMed ID

  • 295364

International Standard Serial Number (ISSN)

  • 0161-5505


  • eng

Conference Location

  • United States