Effect of cardiopulmonary bypass on gastrointestinal perfusion and function.


Journal Article

Gastric mucosal tonometry was used to determine the adequacy of gastrointestinal perfusion in 10 patients undergoing elective myocardial revascularization. Patients were prospectively randomized to receive either pulsatile or nonpulsatile flow during cardiopulmonary bypass. All patients showed a reduction in gastric mucosal perfusion during bypass, manifested by a reduction in the gastric mucosal pH, which occurred independently of variations in the arterial pH. In the group of patients receiving nonpulsatile flow, this reduction was significantly greater (p < 0.05). Cardiopulmonary bypass using nonpulsatile flow is associated with the development of a gastric mucosal acidosis, which may have implications for the development of postoperative complications.

Full Text

Cited Authors

  • Gaer, JA; Shaw, AD; Wild, R; Swift, RI; Munsch, CM; Smith, PL; Taylor, KM

Published Date

  • February 1994

Published In

Volume / Issue

  • 57 / 2

Start / End Page

  • 371 - 375

PubMed ID

  • 8311598

Pubmed Central ID

  • 8311598

International Standard Serial Number (ISSN)

  • 0003-4975

Digital Object Identifier (DOI)

  • 10.1016/0003-4975(94)90999-7


  • eng

Conference Location

  • Netherlands