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Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia.

Publication ,  Journal Article
Robertson, K; Douglas, MJ; McMorland, GH
Published in: Can Anaesth Soc J
September 1985

Using a double-bolus technique, the efficacy and safety of epidural fentanyl with and without epinephrine 1:400,000 for post-Caesarean section analgesia was examined in 30 patients. The addition of 25 micrograms epinephrine to the fentanyl (100 micrograms) did not potentiate the speed of onset but did significantly prolong the duration of action of the second dose. The only side effect encountered was pruritus, which was significantly increased (from 17-44 per cent) when epinephrine was added. The results indicate a clinical advantage of prolonging the duration of action of fentanyl for post-Caesarean Section analgesia with the addition of epinephrine, but the cumbersome and time-consuming nature of a double-bolus technique limits its clinical value. The relative safety of epidural fentanyl with and without epinephrine was confirmed by the absence of respiratory depression, drowsiness or hypotension in all patients.

Duke Scholars

Published In

Can Anaesth Soc J

DOI

ISSN

0008-2856

Publication Date

September 1985

Volume

32

Issue

5

Start / End Page

502 / 505

Location

Canada

Related Subject Headings

  • Time Factors
  • Pregnancy
  • Pain, Postoperative
  • Humans
  • Fentanyl
  • Female
  • Epinephrine
  • Drug Combinations
  • Cesarean Section
  • Anesthesia, Epidural
 

Citation

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Robertson, K., Douglas, M. J., & McMorland, G. H. (1985). Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia. Can Anaesth Soc J, 32(5), 502–505. https://doi.org/10.1007/BF03010800
Robertson, K., M. J. Douglas, and G. H. McMorland. “Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia.Can Anaesth Soc J 32, no. 5 (September 1985): 502–5. https://doi.org/10.1007/BF03010800.
Robertson K, Douglas MJ, McMorland GH. Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia. Can Anaesth Soc J. 1985 Sep;32(5):502–5.
Robertson, K., et al. “Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia.Can Anaesth Soc J, vol. 32, no. 5, Sept. 1985, pp. 502–05. Pubmed, doi:10.1007/BF03010800.
Robertson K, Douglas MJ, McMorland GH. Epidural fentanyl, with and without epinephrine for post-Caesarean section analgesia. Can Anaesth Soc J. 1985 Sep;32(5):502–505.

Published In

Can Anaesth Soc J

DOI

ISSN

0008-2856

Publication Date

September 1985

Volume

32

Issue

5

Start / End Page

502 / 505

Location

Canada

Related Subject Headings

  • Time Factors
  • Pregnancy
  • Pain, Postoperative
  • Humans
  • Fentanyl
  • Female
  • Epinephrine
  • Drug Combinations
  • Cesarean Section
  • Anesthesia, Epidural