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The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass.

Publication ,  Journal Article
Welsby, IJ; Bennett-Guerrero, E; Atwell, D; White, WD; Newman, MF; Smith, PK; Mythen, MG
Published in: Anesth Analg
May 2002

UNLABELLED: Outcome after cardiac surgery varies depending on complication type. We therefore sought to determine the association between complication type, mortality, and length of stay in a large series of patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Multivariate logistic regression was used to test for differences between complication types in mortality and prolonged length of stay (>10 days) while controlling for preoperative and intraoperative risk factors. In 2609 consecutive cardiac surgical patients requiring CPB, the mortality rate was 3.6%; 36.5% had one or more complications, and 15.7% experienced an adverse outcome (death or prolonged length of stay). Multivariate logistic regression demonstrated that complication type was significantly associated with adverse outcome (P < 0.001) independent of Parsonnet score and CPB time (c-index = 0.80). The development of noncardiac complications only (Group NC) and cardiac complications with other organ involvement (Group B) significantly increased mortality and hospital and intensive care unit length of stay (P < 0.001) when compared with cardiac complications only (Group C). The incidences of adverse outcome in Groups C, NC, and B were 15%, 43%, and 67%, respectively; the mortality rates were 3%, 7%, and 20%, respectively. All these intergroup comparisons were significantly different (adjusted P < 0.05). Complications involving organs other than the heart appear to be more deleterious than cardiac complications alone, underscoring the need for strategies to reduce noncardiac complications. IMPLICATIONS: Complications, particularly when they involve organs other than just the heart, increase mortality and prolong the length of hospital stay after heart surgery, independent of a patient's preoperative risk factors and the duration of cardiopulmonary bypass. Strategies aimed at preventing damage to other organs during cardiac surgery need to be improved.

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Published In

Anesth Analg

DOI

ISSN

0003-2999

Publication Date

May 2002

Volume

94

Issue

5

Start / End Page

1072 / 1078

Location

United States

Related Subject Headings

  • Time Factors
  • Postoperative Complications
  • Middle Aged
  • Male
  • Length of Stay
  • Humans
  • Female
  • Cardiopulmonary Bypass
  • Cardiac Surgical Procedures
  • Anesthesiology
 

Citation

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ICMJE
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Welsby, I. J., Bennett-Guerrero, E., Atwell, D., White, W. D., Newman, M. F., Smith, P. K., & Mythen, M. G. (2002). The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass. Anesth Analg, 94(5), 1072–1078. https://doi.org/10.1097/00000539-200205000-00004
Welsby, Ian J., Elliott Bennett-Guerrero, Darryl Atwell, William D. White, Mark F. Newman, Peter K. Smith, and Michael G. Mythen. “The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass.Anesth Analg 94, no. 5 (May 2002): 1072–78. https://doi.org/10.1097/00000539-200205000-00004.
Welsby IJ, Bennett-Guerrero E, Atwell D, White WD, Newman MF, Smith PK, et al. The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass. Anesth Analg. 2002 May;94(5):1072–8.
Welsby, Ian J., et al. “The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass.Anesth Analg, vol. 94, no. 5, May 2002, pp. 1072–78. Pubmed, doi:10.1097/00000539-200205000-00004.
Welsby IJ, Bennett-Guerrero E, Atwell D, White WD, Newman MF, Smith PK, Mythen MG. The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass. Anesth Analg. 2002 May;94(5):1072–1078.

Published In

Anesth Analg

DOI

ISSN

0003-2999

Publication Date

May 2002

Volume

94

Issue

5

Start / End Page

1072 / 1078

Location

United States

Related Subject Headings

  • Time Factors
  • Postoperative Complications
  • Middle Aged
  • Male
  • Length of Stay
  • Humans
  • Female
  • Cardiopulmonary Bypass
  • Cardiac Surgical Procedures
  • Anesthesiology