Cyclosporin A therapy for Wegener's granulomatosis.

Journal Article (Journal Article)

Five patients with active Wegener's granulomatosis were treated with the immunosuppressive agent Cyclosporin A, along with low dose prednisone. All five patients had previously taken cyclophosphamide, but further treatment with this agent was not desired, either due to patient choice, drug toxicity or malignancy. In initial doses of up to 5mg/kg/day, CyA showed efficacy but when lowered to 1-2mg/kg/day, mild disease flares occurred. CyA may provide an alternative to traditional therapy in selected patients with WG.

Full Text

Duke Authors

Cited Authors

  • Allen, NB; Caldwell, DS; Rice, JR; McCallum, RM

Published Date

  • 1993

Published In

Volume / Issue

  • 336 /

Start / End Page

  • 473 - 476

PubMed ID

  • 8296660

International Standard Serial Number (ISSN)

  • 0065-2598

Digital Object Identifier (DOI)

  • 10.1007/978-1-4757-9182-2_85

Language

  • eng

Conference Location

  • United States