Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.

Journal Article (Journal Article;Review)

Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy.

Full Text

Duke Authors

Cited Authors

  • Freedman, NJ; Lefkowitz, RJ

Published Date

  • May 2004

Published In

Volume / Issue

  • 113 / 10

Start / End Page

  • 1379 - 1382

PubMed ID

  • 15146232

Pubmed Central ID

  • PMC406535

International Standard Serial Number (ISSN)

  • 0021-9738

Digital Object Identifier (DOI)

  • 10.1172/JCI21748


  • eng

Conference Location

  • United States