Remodeled cardiac calcium channels.

Journal Article (Review)

Cardiac calcium channels play a pivotal role in the proper functioning of cardiac cells. In response to various pathologic stimuli, they become remodeled, changing how they function, as they adapt to their new environment. Specific features of remodeled channels depend upon the particular disease state. This review will summarize what is known about remodeled cardiac calcium channels in three disease states: hypertrophy, heart failure and atrial fibrillation. In addition, it will review the recent advances made in our understanding of the function of the various molecular building blocks that contribute to the proper functioning of the cardiac calcium channel.

Full Text

Duke Authors

Cited Authors

  • Pitt, GS; Dun, W; Boyden, PA

Published Date

  • September 2006

Published In

Volume / Issue

  • 41 / 3

Start / End Page

  • 373 - 388

PubMed ID

  • 16901502

International Standard Serial Number (ISSN)

  • 0022-2828

Digital Object Identifier (DOI)

  • 10.1016/j.yjmcc.2006.06.071

Language

  • eng

Conference Location

  • England