Well differentiated astrocytoma occurring nine years after radiation therapy for medulloblastoma.


Journal Article (Review)

Conventional treatment for medulloblastoma includes surgical resection followed by craniospinal irradiation, with the potential risk of subsequent radiotherapy-induced secondary neoplasms. We report a 23-year-old woman previously irradiated nine years earlier for a cerebellar medulloblastoma who developed a new enhancing lesion in the primary radiation field four weeks following completion of high dose chemotherapy with bone marrow transplantation for recurrent disease. Resection of this lesion revealed a low grade glioma with no evidence of recurrent medulloblastoma.

Full Text

Duke Authors

Cited Authors

  • Osumi, AK; Mclendon, RE; Tien, RD; Friedman, HS; Graham, M; Hockenberger, B; Halperin, EC; Oakes, WJ

Published Date

  • September 1, 1994

Published In

Volume / Issue

  • 13 / 5

Start / End Page

  • 281 - 285

PubMed ID

  • 7805312

Pubmed Central ID

  • 7805312

International Standard Serial Number (ISSN)

  • 0722-5091


  • eng

Conference Location

  • Germany