The application of monoclonal antibodies in the cytologic evaluation of tumors.

Journal Article (Journal Article;Review)

The focus of this review has been the application of MAbs as adjuncts in the interpretation of cytology specimens. It is evident that most if not all of the MAbs studied thus far are neither completely tumor-specific nor -sensitive; however, when used to address a directed clinical question, they may be "operationally specific." More important, there continues to be no current substitute for the understanding and practice of sound diagnostic cytopathologic principles. Ultimately, the application of MAbs resides in the importance of tumor-associated antigen expression and phenotyping of tumors with therapeutic and prognostic implications.

Full Text

Duke Authors

Cited Authors

  • Szpak, C; McLendon, RE; Simpson, JF; Thor, A; Johnston, WW

Published Date

  • March 1990

Published In

Volume / Issue

  • 10 / 1

Start / End Page

  • 77 - 103

PubMed ID

  • 2184981

International Standard Serial Number (ISSN)

  • 0272-2712


  • eng

Conference Location

  • United States