The application of monoclonal antibodies in the cytologic evaluation of tumors.
Publication
, Journal Article
Szpak, C; McLendon, RE; Simpson, JF; Thor, A; Johnston, WW
Published in: Clin Lab Med
March 1990
The focus of this review has been the application of MAbs as adjuncts in the interpretation of cytology specimens. It is evident that most if not all of the MAbs studied thus far are neither completely tumor-specific nor -sensitive; however, when used to address a directed clinical question, they may be "operationally specific." More important, there continues to be no current substitute for the understanding and practice of sound diagnostic cytopathologic principles. Ultimately, the application of MAbs resides in the importance of tumor-associated antigen expression and phenotyping of tumors with therapeutic and prognostic implications.
Duke Scholars
Published In
Clin Lab Med
ISSN
0272-2712
Publication Date
March 1990
Volume
10
Issue
1
Start / End Page
77 / 103
Location
United States
Related Subject Headings
- Peritoneal Lavage
- Pathology
- Neoplasms
- Humans
- Exudates and Transudates
- Epithelium
- Diagnosis, Differential
- Cytodiagnosis
- Biopsy, Needle
- Biomarkers, Tumor
Citation
APA
Chicago
ICMJE
MLA
NLM
Szpak, C., McLendon, R. E., Simpson, J. F., Thor, A., & Johnston, W. W. (1990). The application of monoclonal antibodies in the cytologic evaluation of tumors. Clin Lab Med, 10(1), 77–103.
Szpak, C., R. E. McLendon, J. F. Simpson, A. Thor, and W. W. Johnston. “The application of monoclonal antibodies in the cytologic evaluation of tumors.” Clin Lab Med 10, no. 1 (March 1990): 77–103.
Szpak C, McLendon RE, Simpson JF, Thor A, Johnston WW. The application of monoclonal antibodies in the cytologic evaluation of tumors. Clin Lab Med. 1990 Mar;10(1):77–103.
Szpak, C., et al. “The application of monoclonal antibodies in the cytologic evaluation of tumors.” Clin Lab Med, vol. 10, no. 1, Mar. 1990, pp. 77–103.
Szpak C, McLendon RE, Simpson JF, Thor A, Johnston WW. The application of monoclonal antibodies in the cytologic evaluation of tumors. Clin Lab Med. 1990 Mar;10(1):77–103.
Published In
Clin Lab Med
ISSN
0272-2712
Publication Date
March 1990
Volume
10
Issue
1
Start / End Page
77 / 103
Location
United States
Related Subject Headings
- Peritoneal Lavage
- Pathology
- Neoplasms
- Humans
- Exudates and Transudates
- Epithelium
- Diagnosis, Differential
- Cytodiagnosis
- Biopsy, Needle
- Biomarkers, Tumor