Immunohistochemistry of the glial fibrillary acidic protein: basic and applied considerations.

Journal Article (Journal Article;Review)

The immunohistochemical localization of glial fibrillary acidic protein has proven its utility in the histologic identification of benign astrocytes and neoplastic cells of glial lineage in the central nervous system. Its application in the developing nervous system has contributed significantly to following the histogenesis of neural tissue. Its identification in various forms of injury and neoplasia has helped in discovering the function of astrocytes in these processes. In diagnostic neuropathology, its greatest contribution has been in the elucidation of the cellular constituencies of neoplasms previously considered of enigmatic origin.

Full Text

Duke Authors

Cited Authors

  • McLendon, RE; Bigner, DD

Published Date

  • July 1994

Published In

Volume / Issue

  • 4 / 3

Start / End Page

  • 221 - 228

PubMed ID

  • 7952263

International Standard Serial Number (ISSN)

  • 1015-6305

Digital Object Identifier (DOI)

  • 10.1111/j.1750-3639.1994.tb00837.x


  • eng

Conference Location

  • Switzerland