Skip to main content

Successful resuscitation after ropivacaine-induced ventricular fibrillation.

Publication ,  Journal Article
Klein, SM; Pierce, T; Rubin, Y; Nielsen, KC; Steele, SM
Published in: Anesth Analg
September 2003

Human data about resuscitation after cardiac arrest from ropivacaine are limited. We present a case of successful cardiopulmonary resuscitation after accidental ropivacaine-induced ventricular fibrillation. A 76-yr-old female patient presented for foot osteotomy. A femoral block was performed using a nerve stimulator, a short bevel needle and 20 mL of 1.5% mepivacaine with 1:400,000 epinephrine. The patient remained relaxed and conversant. Five minutes later, an anterior sciatic block was done with 0.5% ropivacaine with 1:400,000 epinephrine for prolonged analgesia. Despite a negative aspiration and incremental injection, the patient developed a tonic-clonic seizure, then gradual widening of the QRS complex, and subsequently ventricular fibrillation. The patient was resuscitated with chest compressions and airway support prior to pharmacologic treatment of defibrillation. Total venous ropivacaine concentration 5 min after the last injection was 3.2 mg/L, free ropivacaine was 0.5 mg/L, and total mepivacaine was 0.22 mg/L. The patient was admitted to the hospital and discharged the next morning without complications. This case demonstrates that techniques used to detect intravascular injection may reduce but not eliminate catastrophic events. Consequently, regional anesthesia using large amounts of local anesthetic should be done in locations with resuscitation equipment and by individuals trained to recognize these complications and begin early treatment.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Anesth Analg

DOI

ISSN

0003-2999

Publication Date

September 2003

Volume

97

Issue

3

Start / End Page

901 / 903

Location

United States

Related Subject Headings

  • Ventricular Fibrillation
  • Seizures
  • Ropivacaine
  • Orthopedic Procedures
  • Nerve Block
  • Humans
  • Foot
  • Female
  • Electrocardiography
  • Cardiopulmonary Resuscitation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Klein, S. M., Pierce, T., Rubin, Y., Nielsen, K. C., & Steele, S. M. (2003). Successful resuscitation after ropivacaine-induced ventricular fibrillation. Anesth Analg, 97(3), 901–903. https://doi.org/10.1213/01.ANE.0000075839.18073.37
Klein, Stephen M., Trenton Pierce, Yair Rubin, Karen C. Nielsen, and Susan M. Steele. “Successful resuscitation after ropivacaine-induced ventricular fibrillation.Anesth Analg 97, no. 3 (September 2003): 901–3. https://doi.org/10.1213/01.ANE.0000075839.18073.37.
Klein SM, Pierce T, Rubin Y, Nielsen KC, Steele SM. Successful resuscitation after ropivacaine-induced ventricular fibrillation. Anesth Analg. 2003 Sep;97(3):901–3.
Klein, Stephen M., et al. “Successful resuscitation after ropivacaine-induced ventricular fibrillation.Anesth Analg, vol. 97, no. 3, Sept. 2003, pp. 901–03. Pubmed, doi:10.1213/01.ANE.0000075839.18073.37.
Klein SM, Pierce T, Rubin Y, Nielsen KC, Steele SM. Successful resuscitation after ropivacaine-induced ventricular fibrillation. Anesth Analg. 2003 Sep;97(3):901–903.

Published In

Anesth Analg

DOI

ISSN

0003-2999

Publication Date

September 2003

Volume

97

Issue

3

Start / End Page

901 / 903

Location

United States

Related Subject Headings

  • Ventricular Fibrillation
  • Seizures
  • Ropivacaine
  • Orthopedic Procedures
  • Nerve Block
  • Humans
  • Foot
  • Female
  • Electrocardiography
  • Cardiopulmonary Resuscitation