Value of serial troponin T measures for early and late risk stratification in patients with acute coronary syndromes. The GUSTO-IIa Investigators.
Published
Journal Article
BACKGROUND: The baseline cardiac troponin T (cTnT) level strongly predicts short-term mortality in acute coronary syndromes, but the added value of later measures to predict short- and long-term outcome and in the context of baseline clinical characteristics is unclear. METHODS AND RESULTS: Relations between baseline, peak, and 8- and 16-hour (late) cTnT results and outcomes were assessed in 734 patients in a GUSTO-IIa substudy. Proportional-hazards models assessed the prognostic information gained from late cTnT when added to a mortality model containing the baseline cTnT result and clinical factors. At baseline, 260 patients were cTnT-positive (>0.1 ng/mL), 323 became positive later, and 151 remained negative (
Full Text
Duke Authors
- Armstrong, Paul Wayne
- Califf, Robert M.
- Granger, Christopher Bull
- Lee, Kerry L.
- Newby, Laura Kristin
- Ohman, Erik Magnus
Cited Authors
- Newby, LK; Christenson, RH; Ohman, EM; Armstrong, PW; Thompson, TD; Lee, KL; Hamm, CW; Katus, HA; Cianciolo, C; Granger, CB; Topol, EJ; Califf, RM
Published Date
- November 1998
Published In
Volume / Issue
- 98 / 18
Start / End Page
- 1853 - 1859
PubMed ID
- 9799204
Pubmed Central ID
- 9799204
Electronic International Standard Serial Number (EISSN)
- 1524-4539
International Standard Serial Number (ISSN)
- 0009-7322
Digital Object Identifier (DOI)
- 10.1161/01.cir.98.18.1853
Language
- eng