ST-segment recovery as an endpoint in acute myocardial infarction trials. Past, present, and future.

Journal Article (Journal Article)

Traditional, comparative acute myocardial infarction trials have used morbidity and mortality as endpoints, requiring large study populations. Left ventricular function and angiographic infarct-related artery patency have, therefore, been used as alternative endpoints. These assessments are costly, risk-laden, and put a large demand on resources not available in every hospital. This has led to an increased interest in noninvasive endpoints for comparative trials. This study describes the history and possibilities of ST-segment recovery analysis as an endpoint in acute myocardial infarction trials.

Full Text

Duke Authors

Cited Authors

  • Veldkamp, RF; Pope, JE; Sawchak, ST; Wagner, GS; Califf, RM; Krucoff, MW

Published Date

  • 1993

Published In

Volume / Issue

  • 26 Suppl /

Start / End Page

  • 256 - 261

PubMed ID

  • 8189135

International Standard Serial Number (ISSN)

  • 0022-0736


  • eng

Conference Location

  • United States