Results of the economic evaluation of the first study. A multinational prospective economic evaluation. FIRST Investigators. Flolan International Randomized Survival Trial.


Journal Article

We present the prospective economic evaluation that served as a secondary endpoint for the FIRST study, a randomized international multicenter trial of patients with severe congestive heart failure. Although the clinical results of this study were disappointing, we demonstrated the feasibility of incorporating prospective economic evaluation in phase III clinical trials.

Full Text

Cited Authors

  • Schulman, KA; Buxton, M; Glick, H; Sculpher, M; Guzman, G; Kong, J; Backhouse, M; Mauskopf, J; Bell, L; Eisenberg, JM

Published Date

  • 1996

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 698 - 713

PubMed ID

  • 9136477

International Standard Serial Number (ISSN)

  • 0266-4623

Digital Object Identifier (DOI)

  • 10.1017/s0266462300010989


  • eng

Conference Location

  • England