Orthotopic liver transplant patients require less postoperative morphine than do patients undergoing hepatic resection.

Journal Article (Journal Article)

STUDY OBJECTIVE: To compare postoperative morphine use, analgesic efficacy, and side effect profiles in patients following orthotopic liver transplantation (OLTx) and liver resection (LR). DESIGN: Retrospective study. SETTING: Liver transplant and liver resection surgery at a university hospital. PATIENTS: 25 ASA physical status I, II, III, and IV patients undergoing OLTx or liver resection. MEASUREMENTS AND MAIN RESULTS: Morphine use was significantly decreased in the OLTx patients at 6,12, 24, 48, and 72 hours following commencement of patient-controlled analgesia. After commencement of patient-controlled analgesia, pain scores were significantly reduced in the OLTx group compared with those in the liver resection group at 6 and 12 hours. CONCLUSIONS: Orthotopic liver transplant patients experienced less pain and used less morphine postoperatively than did liver resection patients.

Full Text

Duke Authors

Cited Authors

  • Moretti, EW; Robertson, KM; Tuttle-Newhall, JE; Clavien, P-A; Gan, T-J

Published Date

  • September 2002

Published In

Volume / Issue

  • 14 / 6

Start / End Page

  • 416 - 420

PubMed ID

  • 12393108

International Standard Serial Number (ISSN)

  • 0952-8180

Digital Object Identifier (DOI)

  • 10.1016/s0952-8180(02)00390-2


  • eng

Conference Location

  • United States