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Identification of sugar isomers by single-molecule force spectroscopy.

Publication ,  Journal Article
Zhang, Q; Marszalek, PE
Published in: Journal of the American Chemical Society
May 2006

The nanomechanical properties of beta-galactan, a 1 --> 4 linked beta-d-galactose polysaccharide, were investigated with AFM-based single-molecule force spectroscopy. AFM captured a unique plateau at 640 pN in the force spectrogram of beta-galactan, which is significantly different than the plateau at 280 pN in the force spectrogram of amylose. Thus, our results demonstrate that force spectroscopy is able to discriminate between sugar isomers in which axial and equatorial bonds at C1 and C4 are swapped.

Duke Scholars

Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

May 2006

Volume

128

Issue

17

Start / End Page

5596 / 5597

Related Subject Headings

  • Spectrum Analysis
  • Isomerism
  • General Chemistry
  • Carbohydrates
  • Carbohydrate Sequence
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zhang, Q., & Marszalek, P. E. (2006). Identification of sugar isomers by single-molecule force spectroscopy. Journal of the American Chemical Society, 128(17), 5596–5597. https://doi.org/10.1021/ja058828e
Zhang, Qingmin, and Piotr E. Marszalek. “Identification of sugar isomers by single-molecule force spectroscopy.Journal of the American Chemical Society 128, no. 17 (May 2006): 5596–97. https://doi.org/10.1021/ja058828e.
Zhang Q, Marszalek PE. Identification of sugar isomers by single-molecule force spectroscopy. Journal of the American Chemical Society. 2006 May;128(17):5596–7.
Zhang, Qingmin, and Piotr E. Marszalek. “Identification of sugar isomers by single-molecule force spectroscopy.Journal of the American Chemical Society, vol. 128, no. 17, May 2006, pp. 5596–97. Epmc, doi:10.1021/ja058828e.
Zhang Q, Marszalek PE. Identification of sugar isomers by single-molecule force spectroscopy. Journal of the American Chemical Society. 2006 May;128(17):5596–5597.
Journal cover image

Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

May 2006

Volume

128

Issue

17

Start / End Page

5596 / 5597

Related Subject Headings

  • Spectrum Analysis
  • Isomerism
  • General Chemistry
  • Carbohydrates
  • Carbohydrate Sequence
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences