Surface-to-surface bridges formed by reversibly assembled polymers.


Journal Article

Self-assembled polymers whose main chains are defined by reversible DNA base pairing form bridges between the tip of an atomic force microscope and substrate. The forces associated with the rupture of these assemblies are independent of polymer bridge length, and they resemble those expected for the isolated associations defining the polymer bridges. The assembly is reversible and is inhibited by a competitive, nonpolymerizing oligonucleotide. Noncomplementary polymer brush layers do not bridge, and therefore, the forces result from specific molecular recognition events. The length distribution of the bridges differs greatly from that of the polymers in solution, and thus the bridging is responsive to the spatial constraints of the environment.

Full Text

Duke Authors

Cited Authors

  • Kersey, FR; Lee, G; Marszalek, P; Craig, SL

Published Date

  • March 2004

Published In

Volume / Issue

  • 126 / 10

Start / End Page

  • 3038 - 3039

PubMed ID

  • 15012119

Pubmed Central ID

  • 15012119

Electronic International Standard Serial Number (EISSN)

  • 1520-5126

International Standard Serial Number (ISSN)

  • 0002-7863

Digital Object Identifier (DOI)

  • 10.1021/ja0499501


  • eng